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Summary
We report on two patients with acute human immunodeficiency virus (HIV) infection,
who developed an infectious mononucleosis-like clinical episode with thrombocytopenia
and granulocytopenia. In both cases we detected the presence of IgG antigranulocyte
antibodies and in one case the presence of IgG, IgM and IgA antiplatelet antibodies.
The mechanisms of these cytopenias are discussed. The association between such autoimmune
cytopenias and acute HIV infection has not been previously reported.
We suggest testing for HIV seroconversion in patients with a seronegative infectious
mononucleosis-like syndrome belonging to groups with a high risk for HIV infection.
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References
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Article info
Publication history
Accepted:
August 12,
1988
Identification
Copyright
© 1989 The British Society for the Study of Infection. Published by Elsevier Inc.
