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Original article| Volume 18, ISSUE 2, P119-124, March 1989

The management of children born to human immunodeficiency virus seropositive women

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      Summary

      Increasing numbers of children born to human immunodeficiency virus (HIV) antibody-positive women are being identified, but guidelines as to their management are lacking. We have therefore established a paediatric counselling and screening clinic for managing such children in Edinburgh. During a period of 3 years, 49 infants and children of 43 HIV seropositive women have been seen. After a median follow-up period of 23 months, four children were found to have clinical evidence of HIV disease which was non-specific and could have been missed had they not been regularly monitored. Thus, close surveillance of infants born to seropositive women is important. Identifying a single clinic where this is done has allowed experience to accumulate on issues beyond the medical management of these infants as well as contributing to the clinical care of infants with symptoms. Based on this experience, we have developed guidelines for managing children born to HIV antibody-positive women.
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      References

      1. HIV infection: Obstetric and perinatal issues. Lancet. i. 1988: 806-807
        • Peutherer JF
        • Edmond E
        • Simmonds P
        • Dickson JD
        • Bath GE
        HTLV III antibody in Edinburgh drug addicts.
        Lancet. 1985; ii: 1129-1130
        • Robertson JR
        • Bucknall ABV
        • Welsby PD
        • et al.
        An epidemic of AIDS related virus (HTLV III/LAV) infection among intravenous drug abusers in a Scottish General Practice.
        Br Med J. 1986; 292: 527-530
        • Brettle RP
        • Davidson J
        • Davidson S
        • et al.
        HTLV III antibodies in an Edinburgh Clinic.
        Lancet. 1986; i: 1099
        • Brettle RP
        • Bissett K
        • Burns S
        • et al.
        Human immunodeficiency virus and drug misuse; the Edinburgh experience.
        Br Med J. 1987; 295: 421-424
        • Bernstein LJ
        • Krieger BZ
        • Novick B
        • Sicklick MJ
        • Rubenstein A
        Bacterial infection in the acquired immunodeficiency syndrome of children.
        Pediatr Infect Dis. 1985; 4: 472-475
        • Williams PE
        • Hague R
        • Yap PL
        • Mok JQ
        • Brettle RP
        • Coutts NA
        • Eden OB
        • Watson JG
        Treatment of human immunodeficiency virus antibody-positive children with intravenous immunoglobulin.
        J Hosp Infect. 1988; 12: 67-73
      2. Black A, Skinner K. Placement of children at risk of HIV infection. In: Batty D, Ed. The Implications of AIDS for children in care. British Agencies for Adoption and Fostering: 36–47.

        • Mok JQ
        • Giaquinto C
        • De Rossi A
        • Grosch-Worner I
        • Ades AE
        • Peckham CS
        Infants born to mothers seropositive for human immunodeficiency virus.
        Lancet. 1987; i: 1164-1168
        • ACIP
        Immunisation of children infected with Human T lymphotrophic virus type III/lymphadenopathy associated virus.
        MMWR. 1986; 35: 595-606
      3. Report of the Royal College of Obstetricians and Gynaecologists Sub Committee on problems associated with AIDS in relation to obstetrics and gynaecology. October 1987
        • Jesson WJ
        • Thorp RW
        • Mortimer PP
        • Oates JK
        Prevalence of anti-HTLV III in UK risk groups 1984/85.
        Lancet. 1986; i: 155