We read with great interest the recent article by Wetzstein et al. that reported the
overall mortality of Mycobacterium genavense infections and impact of antimycobacterial therapy.
1
Nontuberculous mycobacteria (NTM), especially from pulmonary specimen, have been
reported increasing globally.
2
The geographical distribution of NTM cases varies significantly
3
and the epidemiology is relatively poorly understood in comparison to the genetically
related Mycobacterium tuberculosis. NTM is also not notifiable and routinely monitored in most settings. For many countries,
microbiological data is not even publicly available.
2
For some regions and continents, the epidemiology has been reviewed, but to our knowledge,
no study has summarized the distribution of species among patients with NTM pulmonary
disease (NTM-PD) in Europe. Therefore, we performed a systematic review of PubMed/MEDLINE,
Embase, Scopus, and Web of Science, on July 10, 2022 to identify studies with species
distribution data among patients with NTM-PD, the most common manifestation, in Europe
(as defined by the WHO regions https://www.who.int/countries). Only studies with data on NTM-PD were eligible for inclusion, regardless of whether
guideline criteria were used, while studies without clinical data (i.e., only microbiology)
were excluded. Among others, we extracted the number of patients fulfilling diagnostic
guideline criteria.To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: March 11, 2023
Accepted:
March 9,
2023
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 The British Infection Association. Published by Elsevier Ltd. All rights reserved.