We read with interest an article published by Peng et al. on the use of metagenomics
next-generation sequencing (mNGS) in immunocompromised patients with suspected pneumonia.
1
Here, we describe the use of NGS for detection of Tropheryma whipplei in respiratory samples collected from patients in our hospital. The clinical, radiological
and microbiological characteristics of these patients were also analyzed.Keywords
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References
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- Clinical impact of next-generation sequencing on laboratory diagnosis of suspected culture-negative meningitis and encephalitis.J Infect. 2022; 85: 573-607https://doi.org/10.1016/j.jinf.2022.08.026
- Tropheryma whipplei detection by Nanopore sequencing in patients with interstitial lung disease.Front Microbiol. 2021; 12760696https://doi.org/10.3389/fmicb.2021.760696
- Tropheryma whipplei detection by metagenomic next-generation sequencing in bronchoalveolar lavage fluid: a cross-sectional study.Front Cell Infect Microbiol. 2022; 12961297https://doi.org/10.3389/fcimb.2022.961297
- Comparison of the respiratory microbiome in healthy nonsmokers and smokers.Am J Respir Crit Care Med. 2013; 187: 1067-1075https://doi.org/10.1164/rccm.201210-1913OC
- Widespread colonization of the lung by Tropheryma whipplei in HIV infection.Am J Respir Crit Care Med. 2013; 187: 1110-1117https://doi.org/10.1164/rccm.201211-2145OC
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Article info
Publication history
Published online: December 08, 2022
Accepted:
December 6,
2022
Identification
Copyright
© 2022 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
