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Letter to the Editor| Volume 86, ISSUE 2, e58-e60, February 2023

Direct prediction of ceftazidime-resistant Stenotrophomonas maltophilia from routine MALDI-TOF mass spectra using machine learning

  • Jiaxin Yu
    Affiliations
    AI Innovation Center, China Medical University Hospital, Taichung, Taiwan
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  • Hsiu-Hsien Lin
    Affiliations
    Department of Laboratory Medicine, China Medical University Hospital, Taichung, Taiwan
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  • Kun-Hao Tseng
    Affiliations
    Department of Laboratory Medicine, China Medical University Hospital, Taichung, Taiwan
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  • Ni Tien
    Affiliations
    Department of Laboratory Medicine, China Medical University Hospital, Taichung, Taiwan

    Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan
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  • Po-Ren Hsueh
    Correspondence
    Corresponding author at: Department of Laboratory Medicine, China Medical University Hospital, Taichung, Taiwan.
    Affiliations
    Department of Laboratory Medicine, China Medical University Hospital, Taichung, Taiwan

    Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan

    School of Medicine, China Medical University, Taichung, Taiwan
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  • Der-Yang Cho
    Correspondence
    Corresponding author at: Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.
    Affiliations
    Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan

    Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan
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Published:September 08, 2022DOI:https://doi.org/10.1016/j.jinf.2022.09.005
      We read with great interest the article by Luo et al. describing the use of six diagnostic models established using machine learning based on routine laboratory indicators in differentiating active tuberculosis from latent tuberculosis infection.
      • Luo Y.
      • Xue Y.
      • Song H.
      • Tang G.
      • Liu W.
      • Bai H.
      • et al.
      Machine learning based on routine laboratory indicators promoting the discrimination between active tuberculosis and latent tuberculosis infection.
      Among the six models they built, the optimal performance was obtained from the gradient boosting machine model (GBM), with a sensitivity of 84.4% and a specificity of 92.7%. They concluded that the GBM model may be of great benefit as a tool for accurate identification of active tuberculosis.

      Keywords

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