Critical evaluation of the methodology used by Wilson-Davies et al., (2020) entitled Concerning the Optigene Direct LAMP assay, and it`s use in at-risk groups and hospital staff”

Published:February 08, 2021DOI:
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      Linked Article

      • Home-based SARS-CoV-2 lateral flow antigen testing in hospital workers
        Journal of InfectionVol. 82Issue 2
        • Preview
          We read with interest the recent paper from Fowler et al. on the use of a reverse transcriptase loop mediated isothermal amplification (RT-LAMP) assay for rapid detection of SARS-CoV-2 infection1 and the subsequent recommendation of its suitability for asymptomatic staff testing.2 Lateral flow device (LFD) antigen tests have also been proposed as rapid point-of-care diagnostics for SARS-CoV-2 infection and have the advantage over the RT-LAMP assay in that they can be self-delivered by healthcare workers at home with immediate results.
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      • Concerning the OptiGene Direct LAMP assay, and it’s use in at-risk groups and hospital staff
        Journal of InfectionVol. 82Issue 2
        • Preview
          The COVID-19 pandemic has triggered an unprecedented demand for diagnostic tests. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly contagious in the pre-symptomatic period, when the viral load is high. In the effort to reduce transmission, for the first time in infection diagnostics history, testing is being aimed not only at symptomatic, but also at asymptomatic individuals, both in the health care setting and in the community.
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