Effect of regular intravenous immunoglobulin therapy on prognosis of severe pneumonia in patients with COVID-19

  • Author Footnotes
    1 These author contributed equally.
    Yun Xie
    Footnotes
    1 These author contributed equally.
    Affiliations
    Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 650 New Songjiang Road, Songjiang, 201600, Shanghai, China
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  • Author Footnotes
    1 These author contributed equally.
    Song Cao
    Footnotes
    1 These author contributed equally.
    Affiliations
    Department of Critical Care Medicine, Wuhan Third Hospital,Wuhan University, 216 Guanshan avenue, Hongshan district, Wuhan, 430070, Hubei, China
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  • Author Footnotes
    1 These author contributed equally.
    Hui Dong
    Footnotes
    1 These author contributed equally.
    Affiliations
    Department of Critical Care Medicine, Wuhan Third Hospital,Wuhan University, 216 Guanshan avenue, Hongshan district, Wuhan, 430070, Hubei, China
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  • Qingyun Li
    Affiliations
    Department of Respiratory, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin two Road, Luwan district, 200020, Shanghai, China
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  • Erzhen Chen
    Affiliations
    Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin two Road, Luwan district, 200020, Shanghai, China
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  • Wenkai Zhang
    Affiliations
    Department of Critical Care Medicine, Wuhan Third Hospital,Wuhan University, 216 Guanshan avenue, Hongshan district, Wuhan, 430070, Hubei, China
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  • Luyu Yang
    Correspondence
    Corresponding authors.
    Affiliations
    Department of Critical Care Medicine, Wuhan Third Hospital,Wuhan University, 216 Guanshan avenue, Hongshan district, Wuhan, 430070, Hubei, China
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  • Shouzhi Fu
    Correspondence
    Corresponding authors.
    Affiliations
    Department of Critical Care Medicine, Wuhan Third Hospital,Wuhan University, 216 Guanshan avenue, Hongshan district, Wuhan, 430070, Hubei, China
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  • Ruilan Wang
    Correspondence
    Corresponding authors.
    Affiliations
    Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 650 New Songjiang Road, Songjiang, 201600, Shanghai, China
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  • Author Footnotes
    1 These author contributed equally.
Published:April 10, 2020DOI:https://doi.org/10.1016/j.jinf.2020.03.044

      Highlights

      • Initiation of IVIG as adjuvant treatment for COVID-19 pneumonia within 48 h of admission to the ICU can reduce the use of mechanical ventilation.
      • Initiation of IVIG as adjuvant treatment for COVID-19 pneumonia within 48 h of admission to the ICU can reduce hospital length of stay and length of stay in ICU.
      • Initiation of IVIG as adjuvant treatment for COVID-19 pneumonia within 48 h of admission to the ICU can reduce 28-day mortality of patients with severe COVID-19 pneumonia.
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