Clinical and laboratory-derived parameters of 119 hospitalized patients with coronavirus disease 2019 in Xiangyang, Hubei Province, China

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    1 These author contributed equally to this article
    Liang Shen
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    Affiliations
    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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    Shichao Li
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    1 These author contributed equally to this article
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    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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    1 These author contributed equally to this article
    Yufang Zhu
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    1 These author contributed equally to this article
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    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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    Jianzhong Zhao
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    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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    Xiaoyong Tang
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    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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  • Huiqin Li
    Affiliations
    The Second Hospital of Shijiazhuang, 050000, China
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  • Hui Xing
    Affiliations
    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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  • Mingqing Lu
    Affiliations
    Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
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  • Christina Frederick
    Affiliations
    Department of Microbiology, Biochemistry and Bio-informatics, Laval University, Quebec City G1V 4G2, Canada
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  • Canping Huang
    Affiliations
    Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
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  • Gary Wong
    Correspondence
    Co-corresponding authors.
    Affiliations
    Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China

    Department of Microbiology-Infectiology and Immunology, Laval University, Quebec City G1V 4G2, Canada
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  • Chunhua Wang
    Correspondence
    Co-corresponding authors.
    Affiliations
    Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, Xiangyang, 441021, China
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  • Jiaming Lan
    Correspondence
    Corresponding author at: CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.
    Affiliations
    Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
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    1 These author contributed equally to this article
Published:April 10, 2020DOI:https://doi.org/10.1016/j.jinf.2020.03.038
      The newly emergent Coronavirus disease 2019 (COVID-19) causes severe viral pneumonia in humans and poses a serious threat to public health worldwide, with cases reported from all 6 permanently inhabited continents. Effective clinical management, based on comprehensive laboratory findings, is critical for improving the survival rates of COVID-19 patients. By now, clinical and epidemiological characteristics of COVID-19 in cities outside of Wuhan, such as Beijing
      • Tian S.
      • Hu N.
      • Lou J.
      • Chen K.
      • Kang X.
      • Xiang Z.
      • et al.
      Characteristics of COVID-19 infection in Beijing.
      and Wenzhou
      • Yang W.
      • Cao Q.
      • Qin L.
      • Wang X.
      • Cheng Z.
      • Pan A.
      • et al.
      Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city, Zhejiang, China.
      are described. However, it is currently unknown whether there are any markers that can be informative of mild vs. severe disease. The objective of this study is to describe the comprehensive clinical characteristics of confirmed patients with COVID-19 and explore the potential markers correlating with prognosis.
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