A highly specific rapid antigen detection assay for on-site diagnosis of MERS

  • Yixin Chen
    Affiliations
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
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  • Kwok-Hung Chan
    Affiliations
    Department of Microbiology, The University of Hong Kong, Hong Kong
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  • Congming Hong
    Affiliations
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
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  • Yahong Kang
    Affiliations
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
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  • Shengxiang Ge
    Affiliations
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
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  • Honglin Chen
    Affiliations
    Department of Microbiology, The University of Hong Kong, Hong Kong
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong
    Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong
    Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310006, China
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  • Emily Y.M. Wong
    Affiliations
    Department of Microbiology, The University of Hong Kong, Hong Kong
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  • Sunitha Joseph
    Affiliations
    Central Veterinary Research Laboratory, Dubai, United Arab Emirates
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  • Nissi Georgy Patteril
    Affiliations
    Central Veterinary Research Laboratory, Dubai, United Arab Emirates
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  • Ulrich Wernery
    Affiliations
    Central Veterinary Research Laboratory, Dubai, United Arab Emirates
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  • Ningshao Xia
    Affiliations
    State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China
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  • Susanna K.P. Lau
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  • Patrick C.Y. Woo
    Correspondence
    Corresponding author. State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong. Tel.: +852 22554892; fax: +852 28551241.
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      Gadsby et al. in this Journal, recently described the clinical utility of molecular diagnostics in identifying Legionella infection in patients with acute LRTI.
      • Gadsby N.J.
      • Helgason K.O.
      • Dickson E.M.
      • Mills J.M.
      • Lindsay D.S.
      • Edwards G.F.
      • et al.
      Molecular diagnosis of Legionella infections – clinical utility of front-line screening as part of a pneumonia diagnostic algorithm.
      We developed a rapid antigen detection assay for on-site diagnosis of MERS, which can be finished in 30 min.
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