Summary
Objective
We aimed to compare the features of intensive care units (ICUs), their antimicrobial
resistance patterns, infection control policies, and distribution of infectious diseases
from central Europe to Mid-West Asia.
Methods
A cross-sectional point prevalence study was performed in 88 ICUs from 12 countries.
Characteristics of ICUs, patient and antibiotic therapy data were collected with a
standard form by infectious diseases specialists.
Results
Out of 749, 305 patients at least with one infectious disease were assessed and 254
patients were reported to have coexistent medical problems. When primary infectious
diseases diagnoses of the patients were evaluated, 69 had community-acquired, 61 had
healthcare-associated, and 176 had hospital-acquired infections. Pneumonia was the
most frequent ICU infection seen in half of the patients. Distribution of frequent
pathogens was as follows: Enteric Gram-negatives (n = 62, 28.8%), Acinetobacter spp. (n = 47, 21.9%), Pseudomonas aeruginosa (n = 29, 13.5%). Multidrug resistance profiles of the infecting microorganisms seem
to have a uniform pattern throughout Southern Europe and Turkey. On the other hand,
active and device-associated infection surveillance was performed in Turkey more than
Iran and Southeastern Europe (p < 0.05). However, designing antibiotic treatment according to culture results was
highest in Southeastern Europe (p < 0.05). The most frequently used antibiotics were carbapenems (n = 92, 30.2%), followed by anti-gram positive agents (vancomycin, teicoplanin, linezolid,
daptomycin, and tigecycline; n = 79, 25.9%), beta-lactam/beta lactamase inhibitors (n = 78, 25.6%), and extended-spectrum cephalosporins (n = 73, 23.9%).
Conclusion
ICU features appears to have similar characteristics from the infectious diseases
perspective, although variability seems to exist in this large geographical area.
Keywords
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Article info
Publication history
Published online: November 21, 2013
Accepted:
November 1,
2013
Identification
Copyright
© 2013 The British Infection Association. Published by Elsevier Inc. All rights reserved.
