Journal of Infection
Volume 64, Issue 1 , Pages 1-18, January 2012

Guidelines for prevention and control of group A streptococcal infection in acute healthcare and maternity settings in the UK

  • Jane A. Steer

      Affiliations

    • Department of Microbiology, Derriford Hospital, Plymouth, UK
  • ,
  • Theresa Lamagni

      Affiliations

    • Healthcare-Associated Infection & Antimicrobial Resistance Department, Health Protection Agency, London, UK
  • ,
  • Brendan Healy

      Affiliations

    • Department of Microbiology, Public Health Wales, Cardiff, UK
  • ,
  • Marina Morgan

      Affiliations

    • Department of Microbiology, Royal Devon and Exeter Hospital, Exeter, UK
  • ,
  • Matthew Dryden

      Affiliations

    • Department of Microbiology, Royal Hampshire County Hospital, Winchester, UK
  • ,
  • Bhargavi Rao

      Affiliations

    • Healthcare-Associated Infection & Antimicrobial Resistance Department, Health Protection Agency, London, UK
  • ,
  • Shiranee Sriskandan

      Affiliations

    • Centre for Infection Prevention & Management, Department of Infectious Diseases, Imperial College, London, UK
  • ,
  • Robert George

      Affiliations

    • Respiratory & Systemic Infections Department, Health Protection Agency, London, UK
  • ,
  • Androulla Efstratiou

      Affiliations

    • Respiratory & Systemic Infections Department, Health Protection Agency, London, UK
  • ,
  • Fiona Baker

      Affiliations

    • Infection Prevention & Control Department, North Devon District Hospital, Barnstaple, UK
  • ,
  • Alex Baker

      Affiliations

    • Communications, Health Protection Agency, London, UK
  • ,
  • Doreen Marsden

      Affiliations

    • Lee Spark NF Foundation, Preston, UK
  • ,
  • Elizabeth Murphy

      Affiliations

    • Occupational Health Department, NHS Grampian Occupational Health Service, Aberdeen, UK
  • ,
  • Carole Fry

      Affiliations

    • Infectious Diseases and Blood Policy, Department of Health, London, UK
  • ,
  • Neil Irvine

      Affiliations

    • Public Health Agency, Northern Ireland, UK
  • ,
  • Rhona Hughes

      Affiliations

    • Obstetrics & Gynaecology, Royal Infirmary, Edinburgh, UK
  • ,
  • Paul Wade

      Affiliations

    • Directorates of Pharmacy and Infection, Guy’s & St. Thomas’ NHS Foundation Trust, London, UK
  • ,
  • Rebecca Cordery

      Affiliations

    • North East and North Central London Health Protection Unit, Health Protection Agency, London, UK
  • ,
  • Amelia Cummins

      Affiliations

    • Essex Health Protection Unit, Health Protection Agency, Witham, UK
  • ,
  • Isabel Oliver

      Affiliations

    • Health Protection Agency, South West, Gloucester, UK
  • ,
  • Mervi Jokinen

      Affiliations

    • Development Department, Royal College of Midwives, UK
  • ,
  • Jim McMenamin

      Affiliations

    • Health Protection Scotland, Glasgow, UK
  • ,
  • Joe Kearney

      Affiliations

    • Health Protection Agency, East of England, Witham, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 0845 241 2266; fax: + 44 0 1376 302278.
    • On behalf of the GAS Guideline Development Working Group.

Accepted 1 November 2011. published online 18 November 2011.

Summary 

Hospital outbreaks of group A streptococcal (GAS) infection can be devastating and occasionally result in the death of previously well patients. Approximately one in ten cases of severe GAS infection is healthcare-associated. This guidance, produced by a multidisciplinary working group, provides an evidence-based systematic approach to the investigation of single cases or outbreaks of healthcare-associated GAS infection in acute care or maternity settings.

The guideline recommends that all cases of GAS infection potentially acquired in hospital or through contact with healthcare or maternity services should be investigated. Healthcare workers, the environment, and other patients are possible sources of transmission. Screening of epidemiologically linked healthcare workers should be considered for healthcare-associated cases of GAS infection where no alternative source is readily identified. Communal facilities, such as baths, bidets and showers, should be cleaned and decontaminated between all patients especially on delivery suites, post-natal wards and other high risk areas. Continuous surveillance is required to identify outbreaks which arise over long periods of time. GAS isolates from in-patients, peri-partum patients, neonates, and post-operative wounds should be saved for six months to facilitate outbreak investigation. These guidelines do not cover diagnosis and treatment of GAS infection which should be discussed with an infection specialist.

Keywords: Group A streptococcus, Infection control, Midwifery, Disease outbreaks, Great Britain

 

PII: S0163-4453(11)00535-4

doi:10.1016/j.jinf.2011.11.001

Journal of Infection
Volume 64, Issue 1 , Pages 1-18, January 2012