Journal of Infection
Volume 60, Issue 3 , Pages 209-217 , March 2010

Phenotypic and molecular characterization of invasive serogroup W135 Neisseria meningitidis strains from 1990 to 2005 in Brazil

  • Ana Paula S. Lemos

      Affiliations

    • Division of Medical Biology, Bacteriology Department, Adolfo Lutz Institute, Av. Dr. Arnaldo 351, São Paulo 01246-902, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: +55 11 30682893; fax: +55 11 30853505.
    • ,
  • Lee H. Harrison

      Affiliations

    • Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, PA, USA
    • ,
  • Melina Lenser

      Affiliations

    • Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, PA, USA
    • ,
  • Claudio T. Sacchi

      Affiliations

    • Division of Medical Biology, Immunology Department, Adolfo Lutz Institute, São Paulo 01246-902, Brazil

,Accepted 25 November 2009.

References 

  1. Harrison LH, Trotter CL, Ramsay ME. Global epidemiology of meningococcal disease. Vaccine. 2009;27S:B51–B63
  2. Moraes JC, Barata RB. Meningococcal disease in São Paulo, Brazil, in the 20th century: epidemiological characteristics. Cad Saúde Pública. 2005;21:1458–1471
  3. De Lemos APS, Yara TI, Gorla MCO, Paiva MV, Souza AL, Gonçalves MIC, et al. Clonal distribution of invasive Neisseria meningitidis serogroup C strains circulating from 1976 to 2005 in Greater São Paulo, Brazil. J Clin Microbiol. 2007;45(4):1266–1273
  4. Sacchi CT, Pessoa LL, Ramos SR, Milagres LG, Camargo MCC, Hidalgo NT, et al. Ongoing group B Neisseria meningitidis epidemic in São Paulo, Brazil, due to increased prevalence of a single clone of the ET- 5 complex. J Clin Microbiol. 1992;30(7):1734–1738
  5. Sacchi CT, Zanella RC, Caugant DA, Frasch CE, Hidalgo NT, Milagres LG, et al. Emergence of a new clone of serogroup C Neisseria meningitidis in São Paulo, Brazil. J Clin Microbiol. 1992;30(5):1282–1286
  6. WHO . Meningococcal disease, serogroup W135. Wkly Epidemiol Rec. 2001;19:141–142
  7. Popovic T, Sacchi CT, Reevers MW, Whitney AM, Mayer LM, Noble CA. Neisseria meningitidis serogroup W135 isolates associated with the ET-37 complex. Emerg Infect Dis. 2000;6(4):428–429
  8. Taha MK, Achtman M, Alonso JM, Greenwood B, Ramsay M, Fox A, et al. Serogroup W135 meningococcal disease in Hajj pilgrims. Lancet. 2000;356(9248):2159
  9. Bertherat E, Yada A, Djingarey MH, Koumare B. Premiere epidemie de grande ampleur provoquee par Neisseria meningitidis W135 en Afrique. Med Trop. 2002;62:301–304
  10. Mayer LW, Reeves MW, Al-Hamdan N, Sacchi CT, Taha MK, Ajello GW, et al. Outbreak of W135 meningococcal disease in 2000: not emergence of a new W135 strain but expansion within the electrophoretic type-37 complex. J Infect Dis. 2002;185(11):1596–1605
  11. Barroso DE, Rebelo MC. Recognition of the epidemiological significance of Neisseria meningitidis capsular serogroup W135 in the Rio de Janeiro region, Brazil. Mem Inst Oswaldo Cruz. 2007;102(6):773–775
  12. Weidlich L, Baethgen LF, Mayer LW, Moraes C, Klein CC, Nunes LS, et al. High prevalence of Neisseria meningitidis hypervirulent lineages and emergence of W135:P1.5,2:ST-11 clone in Southern Brazil. J Infect. 2008;57:324–331
  13. Efron AM, Sorhouet C, Salcedo C, Vázquez, JA, Regueira M. Significant increase of serogroup W135 invasive Neisseria meningitidis strains in Argentina: a new epidemiological feature of the region. In: Proceedings of the 16th International Pathogenic Neisseria Conference; 2008.
  14. Wedege E, Hoiby EA, Rosenqvist E, Froholm LO. Serotyping and subtyping of Neisseria meningitidis isolates by co-agglutination, dot-blotting and ELISA. J Med Microbiol. 1990;31(3):195–201
  15. Feavers IM, Gray SJ, Urwin R, Russel JE, Bygraves JA, Kaczmarski EB, et al. Multilocus sequence typing and antigen gene sequencing in the investigation of a meningococcal disease outbreak. J Clin Microbiol. 1999;37(12):3883–3887
  16. Harrison LH, Jolley KA, Schutt KA, Marsh JW, O'Leary M, Sanza LT, et al. Antigenic shift and increased incidence of meningococcal disease. J Infect Dis. 2006;193(9):1266–1274
  17. Russel JE, Jolley KA, Feavers IM, Maiden MC, Suker J. PorA variable regions of Neisseria meningitidis. Emerg Infect Dis. 2004;10(4):674–678
  18. Thompson EA, Feavers IM, Maiden MC. Antigenic diversity of meningococcal enterobactin receptor FetA, a vaccine component. Microbiology. 2003;149:1849–1858
  19. Urwin R, Feavers IM, Jones DM, Maiden MC, Fox AJ. Molecular variation of meningococcal serotype 4 antigen genes. Epidemiol Infect. 1998;121(1):95–101
  20. Maiden MC, Bygraves JA, Feil E, Morelli G, Russel JE, Urwin R, et al. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci U S A. 1998;95(6):3140–3145
  21. Feil EJ, Li BC, Aanensen DM, Hanage WP, Spratt BG. eBurst: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence data. J Bacteriol. 2004;186:1518–1530
  22. Sacchi CT, Whitney AM, Reeves MW, Mayer LW, Popovic T. Sequence diversity of Neisseria meningitidis 16S rRNA genes and use of 16S rRNA gene sequencing as a molecular subtyping tool. J Clin Microbiol. 2002;40(12):4520–4527
  23. Popovic T, Schmink S, Rosenstein NA, Ajello GW, Reeves MW, Plikaytis B, et al. Evaluation of pulsed-field gel electrophoresis in epidemiological investigations of meningococcal disease outbreaks caused by Neisseria meningitidis serogroup C. J Clin Microbiol. 2001;39(1):75–85
  24. Taha MK, Giorgini D, Ducos-Galand M, Alonso JM. Continuing diversification of Neisseria meningitidis W135 as a primary cause of meningococcal disease after emergence of the serogroup in 2000. J Clin Microbiol. 2004;42(9):4158–4163
  25. Moore PS, Reeves MW, Schhwartz B, Gelin B, Broome CV. Intercontinental spread of an epidemic group A Neisseria meningitidis strain. Lancet. 1989;2(8657):260–263
  26. Moore PS, Harrison LH, Telzak EE, Ajello GW, Broome CV. Group A meningococcal carriage in travelers returning from Saudi Arabia. J Am Med Assoc. 1998;260(11):2686–2689
  27. Dull PM, Abdelwahab J, Sacchi CT, Becker M, Noble CA, Barnett GA, et al. Neisseria meningitidis serogroup W-135 carriage among US travelers to the 2001 Hajj. J Infect Dis. 2005;191:33–39doi:1.1086/425927
  28. Apicella MA. Extrameningeal complications of Neisseria meningitidis serogroup W135 infection. Clin Infect Dis. 2004;38:1638–1639
  29. Hahné SJ, Gray SJ, Aguilera J-F, Crowcroft NS, Nichols T, Kaczmarski E, et al. W135 meningococcal disease in England and Wales associated with Hajj 2000 and 2001. Lancet. 2002;359(9306):582–583
  30. Sacchi CT, Lemos APS, Camargo MCC, Whitney AM, Melles CEA, Solari CA, et al. Meningococcal disease caused by Neisseria meningitidis serogroup B serotype 4 in São Paulo, Brazil, 1990 to 1996. Rev Inst Med Trop São Paulo. 1998;40(2):65–70
  31. Sacchi CT, Tondella MLC, Lemos APS, Gorla MCO, Berto DB, Kumiochi NH, et al. Characterization of epidemic Neisseria meningitidis serogroup C strains in several Brazilian states. J Clin Microbiol. 1994;32(7):1783–1787
  32. Russel JE, Urwin R, Gray SJ, Fox AJ, Feavers IM, Maiden MCJ. Molecular epidemiology of meningococcal disease in England and Wales 1975–1995, before the introduction of serogroup C conjugate vaccines. Microbiology. 2008;154:1170–1177
  33. Urwin R, Russel JE, Thompson EAL, Holmes EC, Feavers IM, Maiden MCJ. Distribution of surface protein variants among hyperinvasive meningococci: implications for vaccine design. Infect Immun. 2004;72(10):5955–5962
  34. Ferreira E, Dias R, Giorgini D, Caniça M, Taha MK. Neisseria meningitidis serogroup W135 in Portugal – presence of the ST-11/ET-37 clonal complex. Pathol Biol. 2007;56:94–96
  35. Molling P, Backman A, Olcén P, Fredlund H. Comparison of serogroup W-135 meningococci isolated in Sweden during a 23-year period and those associated with a recent Hajj pilgrimage. J Clin Microbiol. 2001;39(7):2695–2699

PII: S0163-4453(09)00398-3

doi: 10.1016/j.jinf.2009.11.014

Journal of Infection
Volume 60, Issue 3 , Pages 209-217 , March 2010

Article Tools

* Image Usage & Resolution