Journal of Infection
Volume 54, Issue 2 , Pages e55-e57, February 2007

Atypical cutaneous manifestation of HSV-2 with Candida albicans co-infection in a patient with HIV-1

Department of Dermatology, University of Rome “La Sapienza” Viale del Policlinico, 155 00161 Rome, Italy

Accepted 29 March 2006.

Summary 

Herpes simplex virus type 2 (HSV-2) infection was one of the first opportunistic infections identified among patients with AIDS. In the literature there are many data suggesting that the natural history of HSV-2 infection is altered in HIV–HSV-2 co-infected patients. Furthermore, a relationship between HIV seropositivity and HBV infection because of their analogous way of transmission is also described. We report the case of a 37-year-old patient who suffered from multiple painful ulcerative lesions of the perianal region. Laboratory examination showed positivity for HIV and HBV infections. In HIV-positive patients perianal HSV-2 can have atypical manifestations, especially if co-infection by Candida albicans occurs.

Keywords: HSV-2, HIV, HBV, Candida albicans, Co-infection

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PII: S0163-4453(06)00137-X

doi:10.1016/j.jinf.2006.03.036

Journal of Infection
Volume 54, Issue 2 , Pages e55-e57, February 2007

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