Hypoglycemia-induced anoxic brain injury possibly associated with levofloxacin

Summary 

Reports linking alterations in blood glucose concentrations with fluoroquinolones, mostly gatifloxacin and ciprofloxacin, have been published. We describe an elderly, non-diabetic patient with steroid-induced hyperglycemia prescribed glyburide who later developed severe hypoglycemia resulting in anoxic brain injury soon after initiating therapy with levofloxacin.

Keywords: Fluoroquinolones, Hypoglycemia, Glyburide